Cheap Flights from Charleston (CHS) to Knoxville (TYS)

Compare Charleston to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

Book the best Knoxville fare with no extra fees

Find the cheapest month to fly from Charleston to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Charleston to Knoxville flights are currently cheapest in June.

Charleston to Knoxville: Alternative routes

Compare routes from Charleston to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Charleston to Knoxville: Flight information

The things to know before you go.
Cheapest flight found£92
Cheapest month to flyJune

Finding cheap flights from Charleston to Knoxville: Frequently asked questions

The best price we found for a return flight from Charleston to Knoxville is £171. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Charleston to Knoxville. But we found flights with one or more stops from £171.
As of April 2026, there are no flights flying from Charleston to Knoxville.
The cheapest month to fly from Charleston to Knoxville is usually May.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Charleston Airport to Knoxville Airport on Thursday, 14 May 2026.
No airlines currently offer direct flights between Charleston Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Breeze Airways offers the cheapest flight tickets to Knoxville.

Flying from Charleston International Airport (CHS) to McGhee Tyson Airport (TYS): what you need to know

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for stress-free travel. Be at the airport with enough time to board your CHS to TYS flight.

  • Flying during a peak month such as July? School holidays and other high seasons can result in longer queues at security. Play things extra safe and arrive up to four hours before an international flight and two hours before a domestic departure.

  • Think about adding a stopover when booking your ticket from Charleston International Airport to McGhee Tyson Airport. Just deselect 'Direct flights only' to break up your trip, or maybe even explore a new city along the way. Here's where you can stop between CHS and TYS:

    • Hartsfield-Jackson Atlanta International Airport

    • Charlotte Douglas International Airport

    • Orlando International Airport

How to find the cheapest flights from Charleston International Airport (CHS) to McGhee Tyson Airport (TYS)

  • £92 is the lowest price for a one-way Charleston International Airport to McGhee Tyson Airport flight. A return flight starts at £171. These fares can change depending on availability.

  • Don't leave things to the last minute. You're more likely to find cheap tickets from CHS to TYS if you book early. Airlines often have some terrific early bird discounts.

  • If you're willing to be flexible with your travel dates, try using the 'Whole month' tool. It'll show you the cheapest price in each month when searching for a flight from Charleston International Airport to McGhee Tyson Airport.

  • Stay on top of deals for cheap flights from CHS to TYS by creating a Price Alert. You'll receive an email or notification through the app when a special offer becomes available.

  • Tailor your trip with filters. Pick your arrival and departure times, airlines and total journey duration. You can also sort the results by 'Best,' 'Fastest' or 'Cheapest' flights from Charleston International Airport to McGhee Tyson Airport.

Handy information about Charleston International Airport (CHS)

  • Charleston International Airport has a strong on-time record, reducing the likelihood of delays. Departures from CHS land on schedule 81.5% of the time.

  • To get to Charleston International Airport from central Charleston, it takes about 30 minutes if you're travelling by car. This depends on traffic, however. It's approximately 13 miles from the airport to the city centre.

  • Taking public transport? You can expect a journey time of around 3 hours 35 minutes.

  • Have an early flight from Charleston International Airport to McGhee Tyson Airport? Avoid rushing to the terminal (and sneak in some extra precious sleep) by picking one of these stays close to CHS:

Arriving at McGhee Tyson Airport (TYS)

  • Book a hotel near TYS if you're on a late Charleston International Airport to McGhee Tyson Airport flight. Pick one of these accommodation options and make your arrival easier:

  • Pick up a McGhee Tyson Airport rental car and discover Knoxville and beyond with your own wheels. Budget, Alamo and Avis are leading providers to choose from here.

  • Lock in the best possible rate by reserving your vehicle from McGhee Tyson Airport around three weeks before your travel date.

Getting from McGhee Tyson Airport (TYS) to central Knoxville

  • You'll find TYS at 2055 Alcoa Highway.

  • From McGhee Tyson Airport, Knoxville is approximately 14 miles away. It takes around 20 minutes to reach the centre by car.

When to fly to McGhee Tyson Airport (TYS)

  • It's time to choose your travel dates for your flight from Charleston International Airport to McGhee Tyson Airport. July is the busiest month to head to Knoxville. If you want a more relaxed vibe, go in February.

  • Lock in your flight from Charleston International Airport to McGhee Tyson Airport for July if you want to go to Knoxville during its warmest month. Expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).

  • If you like cooler conditions, look for a cheap ticket from CHS to TYS in January. Average temperatures are between -6ºC (21ºF) and 11ºC (52ºF) then.

Explore more of United States

  • Knoxville has plenty to offer, but there are so many other corners of United States just waiting to be explored. About 280 miles north of Knoxville, a visit to Columbus will fill your itinerary to the brim. Start with popular sights like Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.

  • If you're eager to discover another major stop in United States, consider Indianapolis, roughly 290 miles north-west of Knoxville. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are key highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.