Cheap Flights from Cali (CLO) to Panama City (PTYA)

Compare Cali to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

Book the best Panama City fare with no extra fees

Flight deals from Cali to Panama City

Looking for a cheap last-minute deal or the best return flight from Cali Airport to Panama City? If you want to travel next month, return fares start from £175. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Cali to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Cali to Panama City flights are currently cheapest in October.

Direct flights from Cali to Panama City

Alternative Cali to Panama City routes

Looking for the cheapest, fastest or easiest route from Cali to Panama City? You could fly into the following airports instead.

Cali to Panama City: Flight information

The things to know before you go.
Cheapest flight found£94
Cheapest month to flyOctober
Average flight time1 hr, 28 mins
Most popular airlineCopa
Average flights per week117

Finding cheap flights from Cali to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Cali to Panama City is £138. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 27 minutes is the average flight time from Cali to Panama City.
Copa, United and KLM fly direct from Cali to Panama City.
As of April 2026, there are 234 flights per week flying from Cali to Panama City.
The cheapest month to fly from Cali to Panama City is usually October.
If you're flying from Cali Airport, the cheapest airport near Panama City is Balboa – which is 3.0 miles away from the centre of Panama City. We've found flights into this airport from £138.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Cali Airport to Panama City on Friday, 16 October 2026.
Yes – the average flight time is 1 hour and 27 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Wingo offers the cheapest flight tickets to Panama City.

Flying from Alfonso Bonilla Aragon International Airport (CLO) to Panama City: what you need to know

  • Expect to be in the air for 1 hour 40 minutes. That's the average duration of a direct flight from Alfonso Bonilla Aragon International Airport to Panama City.

  • Panama City and Cali (where Alfonso Bonilla Aragon International Airport is located) are both in the UTC-5 timezone. That means you won't have to change your watch on arrival.

  • With 28 flights a week between the two airports, Alfonso Bonilla Aragon International Airport (CLO) to Panama City Tocumen International Airport (PTY) is the most popular route. Copa Airlines operates the earliest flight at 04:40. If you prefer to make the most of your day before taking off, the last departure from CLO to PTY is with Copa Airlines at 18:16.

  • Give yourself enough time to make your CLO to Panama City flight. As a general rule, turn up two hours before international departures and an hour ahead for domestic flights.

  • Flying during a peak month such as July? School holidays and other popular periods can lead to longer queues and delays at security. Be extra cautious and arrive up to four hours ahead of an international flight and two hours before domestic departures.

  • You can book a direct Alfonso Bonilla Aragon International Airport to Panama City ticket. Begin your journey at CLO and end it at Panama City Tocumen International Airport (PTY).

  • Look out for promotions from Copa Airlines. This airline operates direct flights from Alfonso Bonilla Aragon International Airport to Panama City.

  • Stopovers are the perfect opportunity to break up your trip and perhaps even tick off a new city. When searching for plane tickets from CLO to Panama City, deselect the 'Direct flights only' box to see where you can visit along the way. Top options include:

    • Bogota El Dorado International Airport (BOG)

    • Medellin Jose Maria Cordova Intl Airport (MDE)

    • Cartagena Rafael Nunez International Airport (CTG)

  • Located around 19 kms (12 miles) from central Cali, CLO can be reached in about 30 minutes by car. The journey on public transport takes roughly 50 minutes.

  • Want a hassle-free start to your journey? Stay near CLO. Whether you're taking an early flight from Alfonso Bonilla Aragon International Airport to Panama City or want to avoid feeling rushed, these hotels have you covered:

  • When it comes to Alfonso Bonilla Aragon International Airport's on-time performance, 72% of flights stick to their scheduled arrival time.

How to find the cheapest flights from Alfonso Bonilla Aragon International Airport (CLO) to Panama City

  • The best price we've seen for a one-way Alfonso Bonilla Aragon International Airport to Panama City flight is £94. The cheapest price for a return flight is £138. Keep in mind fares can change due to availability at the time of booking.

  • Booking early is often the key to scoring a cheap flight from CLO to Panama City. Flight prices rise as demand increases, so the nearer your departure date, the more you'll likely spend on your ticket.

  • Scoring cheap tickets from Alfonso Bonilla Aragon International Airport to Panama City is more likely if you're flexible with your trip dates. Use the 'Whole month' tool to access the lowest prices throughout the month and land an incredible deal.

  • Locking in a cheap flight from CLO to Panama City is a breeze with Price Alerts. Simply set up one of these automatic notifications and we'll notify you as soon as a cheaper option becomes available.

  • Snag an affordable flight from Alfonso Bonilla Aragon International Airport to Panama City with the help of our filters. Select your preferred duration, number of stops and airlines, then sort the results by 'Cheapest' for the best deals.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

  • The distance from Panama City Tocumen International Airport (PTY) to central Panama City is roughly 24 kms (15 miles). It takes around 35 minutes to reach the centre driving.

  • It typically takes 50 minutes to get there using public transport.

  • Book a hotel near PTY if you have a late flight from Alfonso Bonilla Aragon International Airport to Panama City. Settle into one of these accommodation options and make your first night all about rest:

  • To get the lowest price, book your vehicle from Panama City Tocumen International Airport around three weeks ahead of your flight from CLO to Panama City.

Panama Pacifico International Airport (BLB)

  • The centre of Panama City is located around 6 kms (4 miles) from Panama Pacifico International Airport (BLB). Once your flight from Alfonso Bonilla Aragon International Airport to Panama City has hit the runway and you've made your way through the terminal, the drive should take about 10 minutes.

  • Travelling by public transport will take about 20 minutes.

  • Hang the 'Do not disturb' sign on your door and relax at a hotel close to BLB. Here are a few options where you can check in after your CLO to Panama City flight:

  • Secure your first choice, not your last resort. Reserving your ride from BLB one week ahead of time often means lower prices and a greater selection of vehicles.

Best time to go to Panama City

  • September is the quietest month for flights from Alfonso Bonilla Aragon International Airport to Panama City, while January is the most popular. Figure out the best time to visit Panama City based on whether you prefer a laid-back vibe or a lively atmosphere.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC and 32ºC. Book your Alfonso Bonilla Aragon International Airport to Panama City plane ticket then if this is the type of weather you enjoy.

  • January has average temperatures of between 22ºC and 31ºC. Look for a cheap ticket from CLO to Panama City around that time if you want to travel when it's cooler.

More about Panama City

  • Start your Panama City trip right by choosing the perfect place to stay. Once you've booked your flight from Alfonso Bonilla Aragon International Airport to Panama City, explore our range of accommodation options including:

  • Metropolitan Cathedral (Catedral Metropolitan) and Casco Viejo are a couple of top attractions to add to your Panama City travel itinerary. Keep the adventure rolling by checking out Independence Square.

Explore more of Panama

  • David is just one of the many places in Panama waiting to be explored after you've experienced Panama City. Around 322 kms (200 miles) away to the west, its top attractions include Museo Antropológico y Etnográfico Dr. Roberto De La Guardia, Raptors To The Rescue and Unachi Botanical garden.

  • Your travels through Panama isn't complete without visiting Santiago de Veraguas. Santiago the Apostle Cathedral, Santiago de Veraguas is just one of the highlights in this destination, which is around 193 kms (120 miles) southwest of Panama City.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.