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Cheap Flights from Guayaquil (GYE) to Panama City (PTYA)

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  3. Guayaquil
  4. Panama City

Compare Guayaquil to Panama City flight deals

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Flight deals from Guayaquil to Panama City

Looking for a cheap last-minute deal or the best return flight from Guayaquil to Panama City? Find the lowest prices on one-way and return tickets right here.
Panama City.£163 per passenger.Departing Sat, 21 Jun, returning Tue, 24 Jun.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Sat, 21 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 24 Jun, arriving in Guayaquil.Price includes taxes and charges.From £163, select.
Sat, 21 JunGYE - PTY with Avianca
1 stop
Tue, 24 JunPTY - GYE with Avianca
1 stop
from £163
Panama City.£164 per passenger.Departing Fri, 1 Aug, returning Thu, 7 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Fri, 1 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 7 Aug, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Fri, 1 AugGYE - PTY with Avianca
1 stop
Thu, 7 AugPTY - GYE with Avianca
1 stop
from £164
Panama City.£164 per passenger.Departing Thu, 28 Aug, returning Mon, 29 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Thu, 28 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 29 Sep, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Thu, 28 AugGYE - PTY with Avianca
1 stop
Mon, 29 SepPTY - GYE with Avianca
1 stop
from £164
Panama City.£164 per passenger.Departing Wed, 1 Oct, returning Sun, 5 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Wed, 1 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 5 Oct, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Wed, 1 OctGYE - PTY with Avianca
1 stop
Sun, 5 OctPTY - GYE with Avianca
1 stop
from £164
Panama City.£164 per passenger.Departing Mon, 28 Jul, returning Fri, 1 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Mon, 28 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 1 Aug, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Mon, 28 JulGYE - PTY with Avianca
1 stop
Fri, 1 AugPTY - GYE with Avianca
1 stop
from £164
Panama City.£164 per passenger.Departing Fri, 18 Jul, returning Tue, 22 Jul.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Fri, 18 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 22 Jul, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Fri, 18 JulGYE - PTY with Avianca
1 stop
Tue, 22 JulPTY - GYE with Avianca
1 stop
from £164
Panama City.£164 per passenger.Departing Sun, 21 Sep, returning Fri, 26 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Sun, 21 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 26 Sep, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Sun, 21 SepGYE - PTY with Avianca
1 stop
Fri, 26 SepPTY - GYE with Avianca
1 stop
from £164
Panama City.£164 per passenger.Departing Mon, 30 Jun, returning Thu, 10 Jul.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Guayaquil on Mon, 30 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 10 Jul, arriving in Guayaquil.Price includes taxes and charges.From £164, select.
Mon, 30 JunGYE - PTY with Avianca
1 stop
Thu, 10 JulPTY - GYE with Avianca
1 stop
from £164
How did we find these deals? The deals you see here are the lowest prices for flight tickets from Guayaquil to Panama City found in the last 4 days, and are subject to change and availability.

The cheapest month to fly from Guayaquil Airport to Panama City

We’re always keeping an eye on fares, to help you find the lowest one in seconds. Check out the Guayaquil Airport to Panama City flight prices forecast over the next 12 months.
Jun
from £163
Jul
from £164
Aug
from £164
Sep
from £164
Oct
from £164
Nov
from £243
Dec
from £250
Jan
from £248
Feb
Find prices
Mar
from £248
Apr
from £281
May
from £252
Cheapest month:June
Most expensive month:April

Direct flights from Guayaquil to Panama City

Alternative Guayaquil to Panama City routes

Looking for the cheapest, fastest or easiest route from Guayaquil to Panama City? You could fly into the following airports instead.

Guayaquil to Panama City: Flight information

The things to know before you go.
Cheapest flight found£163
Cheapest month to flyJune
Average flight time2 hrs, 11 mins
Most popular airlineCopa
Average flights per week90

Finding cheap flights from Guayaquil to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Guayaquil to Panama City is £163. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 11 minutes is the average flight time from Guayaquil to Panama City.
Copa, United and KLM fly direct from Guayaquil to Panama City.
As of June 2025, there are 180 flights per week flying from Guayaquil to Panama City.
The cheapest month to fly from Guayaquil to Panama City is usually June 2025.
If you're flying from Guayaquil Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 11.1 miles away from the centre of Panama City. We've found flights into this airport from £163.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Guayaquil Airport to Panama City on Saturday, 21 June 2025.
Yes – the average flight time is 2 hours and 11 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In June, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Avianca and Copa offer the cheapest flight tickets to Panama City.

Travelling from Jose Joaquin de Olmedo Airport (GYE) to Panama City: what you need to know

  • The average time for a direct flight from Jose Joaquin de Olmedo Airport to Panama City is 2 hours 15 minutes.

  • Panama City's timezone is UTC-5, which is the same as Guayaquil (the location of Jose Joaquin de Olmedo Airport).

  • With 36 weekly flights between the two airports, Jose Joaquin de Olmedo Airport (GYE) to Tocumen International Airport (PTY) is the busiest route. Copa Airlines operates the earliest flight at 04:26. If you prefer to make the most of your day before taking off, the last flight from GYE to PTY is with Copa Airlines at 18:49.

  • Give yourself enough time to get on your GYE to Panama City flight. It's generally best to arrive two hours before international departures and an hour ahead for domestic flights.

  • If you're jetting off during a major holiday or another peak period, give yourself more time. A good general rule is two hours before domestic flights and up to four hours before international departures. Queues at security and check-in will be longer.

  • Direct Jose Joaquin de Olmedo Airport to Panama City tickets are available for booking. Tocumen International Airport (PTY) is where you'll complete your journey.

  • Book your ticket with Copa Airlines. This popular carrier operates direct flights from Jose Joaquin de Olmedo Airport to Panama City.

  • Consider adding a stopover to potentially unlock a cheaper plane ticket from GYE to Panama City. Simply uncheck 'Direct flights only' during your search. Take a break (and maybe save some cash) by stopping at one of these airports:

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

    • Mariscal Sucre International Airport (UIO)

  • GYE is about 3 miles from central Guayaquil. If you're catching a cab, ride-sharing or driving from the centre, it'll take 10 minutes or so to get there, depending on the traffic. If you're using public transport, expect the journey time to be around 20 minutes.

  • Looking for a hotel near GYE? If you've booked an early flight from Jose Joaquin de Olmedo Airport to Panama City, these accommodation options will get you from your pillow to the plane in no time:

    • Oro Verde Guayaquil

    • GH Galeria Hotel

    • Wyndham Garden Guayaquil

  • Jose Joaquin de Olmedo Airport has a strong on-time record, reducing your chances of a delayed flight. Departures from GYE make it to their destination as scheduled 89.07% of the time.

How to find the cheapest flights from Jose Joaquin de Olmedo Airport (GYE) to Panama City

  • The best price we've found for a one-way Jose Joaquin de Olmedo Airport to Panama City flight is £76. The cheapest price for a return flight is £163. Bear in mind fares can change due to availability at the time of booking.

  • Book one month before you want to fly. Pricing trends show that this is the ideal window for finding cheap flights from GYE to Panama City.

  • Organise your trip for May. That's the best month for landing the biggest deals on Jose Joaquin de Olmedo Airport to Panama City tickets. If you're flexible on when you fly, use the 'Whole month' tool to find the cheapest price across each month.

  • You don't need to keep looking every day to find out if fares have dropped when you set up a Price Alert. We'll update you as soon as there's an even bigger deal on cheap flights from GYE to Panama City.

  • Find a cheap flight from Jose Joaquin de Olmedo Airport to Panama City with the help of our filters. Choose your preferred duration, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) is around 13 miles from the centre of Panama City. If you're getting a cab or a ride-share, the drive will take roughly 20 minutes.

  • Travelling by public transport takes about 1 hour 5 minutes.

  • Consider staying in a hotel near PTY if you have a late flight from Jose Joaquin de Olmedo Airport to Panama City. Settle into one of these accommodation options and make your first night all about catching up on rest:

    • Crowne Plaza Panama Airport

    • Riande Aeropuerto Hotel Casino

    • Express Inn PTY Aeropuerto Internacional Panama

  • Explore without limits with a Tocumen International Airport rental car. Pick up your wheels from Avis, Dollar or MEX and venture far and wide through Panama City and beyond.

  • Lock in the lowest price by booking your vehicle from Tocumen International Airport about three weeks ahead of your flight from GYE to Panama City.

Marcos A. Gelabert International Airport (PAC)

  • After your flight from Jose Joaquin de Olmedo Airport to Panama City has landed, you can get to the city centre in around 5 minutes by car. Central Panama City is roughly 1 mile from Marcos A. Gelabert International Airport (PAC).

  • If you choose to travel on public transport, the journey will take you 25 minutes or so.

  • After stepping off your GYE to Panama City flight, tuck yourself in at a hotel near PAC. These are some great accommodation options that'll help you sink into relaxation mode:

    • Novotel Panama City

    • Riu Plaza Panamá

    • Hotel Las Americas Golden Tower Panamá

  • Thrifty, Avis and Alamo make collecting a Marcos A. Gelabert International Airport rental car quick and easy. These trusted providers are located in or around the terminal and will have you on the road before long.

  • Secure your first choice, not your last resort. Booking your ride from PAC three weeks ahead of time often means better deals and a wider selection of vehicles.

Panama Pacifico Airport (BLB)

  • Hop off your flight from Jose Joaquin de Olmedo Airport to Panama City and head straight for your hotel or jump right into sightseeing. The centre of Panama City is around 10 miles from Panama Pacifico Airport (BLB) and usually takes 20 minutes to drive there.

  • If you don't want to make your way to the centre, head for a hotel close to BLB. Get comfortable at one of these stays after your GYE to Panama City flight:

    • Radisson Hotel Panama Canal

    • The Westin Playa Bonita Panama

    • Pacific Coast Hotel

  • Whether you're looking for an economy for a solo trip or a roomy SUV to fit the whole crew comfortably, you'll find the ideal Panama Pacifico Airport rental car for your needs. Check out the range of wheels available from companies such as Sixt, Dollar and Thrifty.

  • If you're after a specific type of vehicle, book your ride from BLB around one week ahead of your flight from Jose Joaquin de Olmedo Airport to Panama City. This gives you a better shot at getting the car you prefer, as well as a better rate.

Best time to go to Panama City

  • Carefully consider your dates before securing your flight from Jose Joaquin de Olmedo Airport to Panama City. The city buzzes during high season, but prices are typically higher and major attractions can be busy. Visit Panama City in the off-season if you like a more relaxed vibe.

  • Lock in a Jose Joaquin de Olmedo Airport to Panama City plane ticket with a departure in March if you're eager to visit the city during its warmest month. Expect temperatures to range from 21ºC (70ºF) to 32ºC (90ºF).

  • February sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Search for a cheap ticket from GYE to Panama City around that time if you want to travel when it's cooler.

More about Panama City

  • Start your Panama City trip off on the right foot by choosing the ideal place to stay. Once you've booked your flight from Jose Joaquin de Olmedo Airport to Panama City, browse our selection of accommodation options including:

    • Novotel Panama City

    • Riu Plaza Panamá

    • Hotel Las Americas Golden Tower Panamá

  • Every great holiday has to include some sightseeing. Casco Viejo, Panama Canal Museum and Cinta Costera are attractions you won't want to skip in Panama City.

Explore more of Panama

  • You've done Panama City, now it's time to explore more of Panama. Journey about 200 miles west to David to check off its popular sights. From Parque Cervantes to Altos del Rio Park and Coquito Hills Park, you've got a jam-packed schedule ahead.

  • If you're ready to explore another well-known destination in Panama, consider Santiago de Veraguas, roughly 120 miles south-west of Panama City. Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios are among the biggest draws.

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Plan the rest of your trip from Guayaquil to Panama City

  • Car hire in Panama City
  • Hotels in Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.

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